HAKEDA, Yoshiyuki: search on Z-Library

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1

Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment

Yoshiyuki Hakeda, Hiroshi Kawaguchi, Marja Hurley, Carol C. Pilbeam, Christine Abreu, Thomas A. Linkhart, Subburaman Mohan, Masayoshi Kumegawa, Lawrence G. Raisz

Journal:

Journal of Cellular Physiology

Year:

1996

Language:

english

File:

PDF, 668 KB

english, 1996

2

Prostaglandin E2 stimulates DNA synthesis by a cyclic AMP-independent pathway in osteoblastic clone MC3T3-E1 cells

Yoshiyuki Hakeda, Takahiko Yoshino, Yoshinori Natakani, Noriyoshi Kurihara, Norihiko Maeda, Masayoshi Kumegawa

Journal:

Journal of Cellular Physiology

Year:

1986

Language:

english

File:

PDF, 1006 KB

english, 1986

3

Stimulatory effect of a phorbol ester on expression of insulin-like growth factor (IGF) binding protein-2 and level of IGF-I receptors in mouse osteoblastic MC3T3-E1 cells

Yoshiyuki Hakeda, Kenji Yoshizawa, Marja Hurley, Hiroshi Kawaguchi, Ken-Ichi Tezuka, Kayo Tanaka, Takuya Satoh, Masayoshi Kumegawa

Journal:

Journal of Cellular Physiology

Year:

1994

Language:

english

File:

PDF, 776 KB

english, 1994

4

Hepatocyte growth factor is involved in formation of osteoclast-like cells mediated by clonal stromal cells (MC3T3-G2/PA6)

Takuya Sato, Yoshiyuki Hakeda, Yuji Yamaguchi, Hiroshi Mano, Ken-Ichi Tezuka, Kunio Matsumoto, Toshikazu Nakamura, Yoshihisa Mori, Kenji Yoshizawa, Koji Sumitani, Hiroaki Kodama, Masayoshi Kumegawa

Journal:

Journal of Cellular Physiology

Year:

1995

Language:

english

File:

PDF, 902 KB

english, 1995

5

Tyro 3 Receptor Tyrosine Kinase and its Ligand, Gas6, Stimulate the Function of Osteoclasts

Yuka S. Nakamura, Yoshiyuki Hakeda, Nobuyuki Takakura, Takashi Kameda, Isao Hamaguchi, Takeshi Miyamoto, Shinji Kakudo, Toru Nakano, Masayoshi Kumegawa, Dr. Toshio Suda

Journal:

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

6

Isolated chick osteocytes stimulate formation and bone-resorbing activity of osteoclast-like cells

Kayo Tanaka, Yuji Yamaguchi, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Metabolism

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

7

Effects of transforming growth factor-β1on formation and activation of osteoclasts

Hiroshi Kamioka, Keishi Ishikawa, Kayo Tanaka, Takuya Sato, Ken-Ichi Tezuka, Kenji Hiura, Koji Sumitani, Yoshiyuki Hakeda, Terushige Kawata, Masayoshi Kumegawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

1995

Language:

english

File:

PDF, 957 KB

english, 1995

8

Isolation of highly enriched rabbit osteoclasts from collagen gels: A new assay system for bone-resorbing activity of mature osteoclasts

Shinji Kakudo, Koshi Miyazawa, Takashi Kameda, Hiroshi Mano, Yoshihisa Mori, Tatsuhisa Yuasa, Yukiya Nakamaru, Miho Shiokawa, Kazuhiro Nagahira, Sachiko Tokunaga, Yoshiyuki Hakeda, Masayoshi Kumegawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

1996

Language:

english

File:

PDF, 1.67 MB

english, 1996

9

Prostaglandins and bone cell activity

Yoshiyuki Hakeda, Masayoshi Kumegawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

1988

Language:

english

File:

PDF, 1.37 MB

english, 1988

10

Action of prostaglandins on clonal osteoblastic MC3T3-E1 cells

Yoshiyuki Hakeda, Mamoru Okawa, Masayoshi Kumegawa

Journal:

Journal of Bone and Mineral Metabolism

Year:

1991

Language:

english

File:

PDF, 674 KB

english, 1991

11

Effect of interleukin 1 beta on osteoblastic clone MC3T3-E1 cells

Eiko Ikeda, Masami Kusaka, Yoshiyuki Hakeda, Kazushige Yokota, Masayoshi Kumegawa, Shozo Yamamoto

Journal:

Calcified Tissue International

Year:

1988

Language:

english

File:

PDF, 452 KB

english, 1988

12

The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage

Yukinao Kobayashi, Seiichi Ueyama, Yoshinori Arai, Yasushi Yoshida, Toshio Kaneda, Takuya Sato, Kitetsu Shin, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Metabolism

Year:

2004

Language:

english

File:

PDF, 262 KB

english, 2004

13

Production of IL-7 is increased in ovariectomized mice, but not RANKL mRNA expression by osteoblasts/stromal cells in bone, and IL-7 enhances generation of osteoclast precursors in vitro

Takuya Sato, Ken Watanabe, Masaaki Masuhara, Naoto Hada, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Metabolism

Year:

2007

Language:

english

File:

PDF, 1.73 MB

english, 2007

14

Protective protein/cathepsin

Masaaki Masuhara, Takuya Sato, Naoto Hada, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

15

Down-Regulation of Gap Junctional Intercellular Communication Between Osteoblastic MC3T3-E1 Cells by Basic Fibroblast Growth Factor and a Phorbol Ester (12-O-Tetradecanoylphorbol-13-Acetate)

Miho Shiokawa-Sawada, Hiroshi Mano, Kooji Hanada, Shinji Kakudo, Takashi Kameda, Koshi Miyazawa, Yukiya Nakamaru, Tatsuhisa Yuasa, Yoshihisa Mori, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 457 KB

english, 1997

16

Direct and Indirect Actions of Fibroblast Growth Factor 2 on Osteoclastic Bone Resorption in Cultures

Hiroshi Kawaguchi, Daichi Chikazu, Kozo Nakamura, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 335 KB

english, 2000

17

Tissue specific expression and differential regulation by 1α,25-dihydroxyvitamin D3 of the calcium-sensing receptor (CaSR) gene in rat kidney, intestine, and calvaria

Harutsugi Abukawa, Hiroshi Mano, Toshiya Arakawa, Yoshiyuki Hakeda, Hiroto Kimura, Masayoshi Kumegawa

Journal:

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

18

Dexamethasone inhibits bone resorption by indirectly inducing apoptosis of the bone-resorbing osteoclasts via the action of osteoblastic cells

Shintaro Warabi, Yomei Tachibana, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

19

Estrogen directly down-regulates the bone-resorbing activity of mature osteoclasts through nuclear estrogen receptor α

Hiroshi Mano, Yoshiyuki Hakeda, Masayoshi Kumegawa

Journal:

Year:

2001

Language:

english

File:

PDF, 106 KB

english, 2001

20

Transient recruitment of osteoclasts and expression of their function in osteopetrotic (op/op) mice by a single injection of macrophage colony-stimulating factor

Hiroaki Kodama, Akira Yamasaki, Moriaki Abe, Shumpei Niida, Yoshiyuki Hakeda, Hiroyuki Kawashima

Journal:

Journal of Bone and Mineral Research

Year:

1993

Language:

english

File:

PDF, 2.46 MB

english, 1993

21

Basic fibroblast growth factor regulates IGF-I binding proteins in the clonal osteoblastic cell line MC3T3-E1

Dr. Marja M. Hurley, Christine Abreu, Yoshiyuki Hakeda

Journal:

Journal of Bone and Mineral Research

Year:

1995

Language:

english

File:

PDF, 1.03 MB

english, 1995

22

Vitamin K2Inhibits Osteoclastic Bone Resorption by Inducing Osteoclast Apoptosis

Takashi Kameda, Koshi Miyazawa, Yoshihisa Mori, Tatsuhisa Yuasa, Miho Shiokawa, Yukiya Nakamaru, Hiroshi Mano, Yoshiyuki Hakeda, Akira Kameda, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 1.25 MB

english, 1996

23

Mammalian Mature Osteoclasts as Estrogen Target Cells

Hiroshi Mano, Tatsuhisa Yuasa, Takashi Kameda, Koshi Miyazawa, Yukiya Nakamaru, Miho Shiokawa, Yoshihisa Mori, Takeo Yamada, Katsunobu Miyata, Hiroyuki Shindo, Hirohiko Azuma, Yoshiyuki Hakeda, Masayo

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 115 KB

english, 1996

24

Concanavalin A Directly Stimulates Bone-Resorbing Activity of Osteoclasts and Their Gene Expression of Cathepsin K/OC-2

Shinji Kakudo, Hiroshi Mano, Miho Shiokawa, Yoshihisa Mori, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 375 KB

english, 1997

25

Calcium-Sensing Receptor in Mature Osteoclasts, Which Are Bone Resorbing Cells

Takashi Kameda, Hiroshi Mano, Yoshiji Yamada, Hiroyuki Takai, Norio Amizuka, Masato Kobori, Naoya Izumi, Hiroyuki Kawashima, Hidehiro Ozawa, Kyoji Ikeda, Akira Kameda, Yoshiyuki Hakeda, Masayoshi Kume

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 447 KB

english, 1998

26

Osteoclastogenesis Inhibitory Factor (OCIF) Directly Inhibits Bone-Resorbing Activity of Isolated Mature Osteoclasts

Yoshiyuki Hakeda, Yukinao Kobayashi, Kyoji Yamaguchi, Hisataka Yasuda, Eisuke Tsuda, Kanji Higashio, Takashi Miyata, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 578 KB

english, 1998

27

Prostaglandin E2 stimulates collagen and non-collagen protein synthesis and prolyl hydroxylase activity in osteoblastic clone MC3T3-E1 cells

Yoshiyuki Hakeda, Yoshinori Nakatani, Noriyoshi Kurihara, Eiko Ikeda, Norihiko Maeda, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 332 KB

english, 1985

28

Existence of parathyroid hormone binding sites on murine hemopoietic blast cells

Yoshiyuki Hakeda, Kenji Hiura, Takuya Sato, Ryo Okazaki, Toshio Matsumoto, Etsuro Ogata, Ryoichi Ishitani, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 390 KB

english, 1989

29

Murine recombinant leukemia inhibitory factor modulates inhibitory effect of 1,25 dihydroxyvitamin D3 on alkaline phosphatase activity in MC3T3-E1 cells

Yoshiyuki Hakeda, Tetsuo Sudo, Seiichi Ishizuka, Kayo Tanaka, Kiyoshi Higashino, Michinori Kusuda, Hiroaki Kodama, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 403 KB

english, 1991

30

Identification of osteopontin in isolated rabbit osteoclasts

Ken-ichi Tezuka, Takuya Sato, Hiroshi Kamioka, Peter J. Nijweide, Kayo Tanaka, Tetsu Matsuo, Mitsue Ohta, Noriyoshi Kurihara, Yoshiyuki Hakeda, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.71 MB

english, 1992

31

Effect of chlorpromazine on pz-peptidase and several other peptidase activities in cloned osteoblastic cells (MC3T3-E1)

Toshiyuki Chikuma, Yoko Ishii, Takeshi Kato, Noriyoshi Kurihara, Yoshiyuki Hakeda, Masayoshi Kumegawa

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 667 KB

english, 1987

32

Effect of transferrin on alkaline phosphatase activity and collagen synthesis in osteoblastic cells derived from newborn mouse calvaria

Mauri Tsunoi, Yoshiyuki Hakeda, Noriyoshi Kurihara, Norihiko Maeda, Nobuo Utsumi, Masayoshi Kumegawa

Journal:

Experimental Cell Research

Year:

1984

Language:

english

File:

PDF, 361 KB

english, 1984

33

Receptor activator of NF-κB ligand-dependent expression of caveolin-1 in osteoclast precursors, and high dependency of osteoclastogenesis on exogenous lipoprotein

Naoto Hada, Mari Okayasu, Junta Ito, Mai Nakayachi, Chiyomi Hayashida, Toshio Kaneda, Noritaka Uchida, Takamichi Muramatsu, Chihiro Koike, Masaaki Masuhara, Takuya Sato, Yoshiyuki Hakeda

Journal:

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

34

Isolation of mouse and human cDNA clones encoding a protein expressed specifically in osteoblasts and brain tissues

Ken-ichi Tezuka, Sunao Takeshita, Yoshiyuki Hakeda, Masayoshi Kumegawa, Reiko Kikuno, Tamotsu Hashimoto-Gotoh

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 669 KB

english, 1990

35

Effect of 1,25-dihydroxyvitamin D3 on alkaline phosphatase activity and collagen synthesis in osteoblastic cells, clone MC3T3-El1

Noriyoshi Kurihara, Katsumi Ikeda, Yoshiyuki Hakeda, Mauri Tsunoi, Norihiko Maeda, Masayoshi Kumegawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 207 KB

english, 1984

36

The unique action for bone metabolism of 1α,25-(OH)2D3-26,23-lactone

Mamoru Kiyoki, Noriyoshi Kurihara, Seiichi Ishizuka, Shigeyuki Ishii, Yoshiyuki Hakeda, Masayoshi Kumegawa, Anthony W. Norman

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 304 KB

english, 1985

37

Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

Mari Nakagawa, Toshio Kaneda, Toshiya Arakawa, Shuichi Morita, Takuya Sato, Takeo Yomada, Koji Hanada, Masayoshi Kumegawa, Yoshiyuki Hakeda

Journal:

Year:

2000

Language:

english

File:

PDF, 204 KB

english, 2000

38

Stimulation of osteoblast proliferation by the cartilage-derived growth promoting factors chondromodulin-I and -II

Yoshihisa Mori, Yuji Hiraki, Chisa Shukunami, Shinji Kakudo, Miho Shiokawa, Masako Kagoshima, Hiroshi Mano, Yoshiyuki Hakeda, Takahide Kurokawa, Fujio Suzuki, Masayoshi Kumegawa

Journal:

Year:

1997

Language:

english

File:

PDF, 479 KB

english, 1997

39

A simple method to assess osteoclast-mediated bone resorption using unfractionated bone cells

Kusuda, Michinori, Hiura, Kenji, Sato, Takuya, Mochizuki, Hiroshi, Nagao, Yoshitaka, Tomura, Michio, Yahiro, Masatoshi, Hakeda, Yoshiyuki, Kawashima, Hiroyuki, Takada, Yukihiro

Journal:

Bone and Mineral

Year:

1992

Language:

english

File:

PDF, 4.32 MB

english, 1992

40

CD38/ADP-Ribosyl Cyclase: A New Role in the Regulation of Osteoclastic Bone Resorption

Li Sun, Olugbenga A. Adebanjo, Baljit S. Moonga, Susanne Corisdeo, Hindupur K. Anandatheerthavarada, Gopa Biswas, Toshiya Arakawa, Yoshiyuki Hakeda, Antoliy Koval, Bali Sodam, Peter J. R. Bevis, A. Ja

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 832 KB

english, 1999

41

Effects of diastereoisomers of 1,25-dihydroxyvitamin D3-26,23-lactone on alkaline phosphatase and collagen synthesis in osteoblastic cells

Ishizuka, Seiichi, Kiyoki, Mamoru, Kurihara, Noriyoshi, Hakeda, Yoshiyuki, Ikeda, Katsumi, Kumegawa, Masayoshi, Norman, Anthony W.

Journal:

Molecular and Cellular Endocrinology

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

42

Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state

Nakayachi, Mai, Ito, Junta, Hayashida, Chiyomi, Ohyama, Yoko, Kakino, Akemi, Okayasu, Mari, Sato, Takuya, Ogasawara, Toru, Kaneda, Toshio, Suda, Naoto, Sawamura, Tatsuya, Hakeda, Yoshiyuki

Journal:

Year:

2015

Language:

english

File:

PDF, 2.20 MB

english, 2015

43

Prostaglandin E 1 and F 2α Stimulate Differentiation and Proliferation, Respectively, of Clonal Osteoblastic MC3T3-E1 Cells by Different Second Messengers in Vitro *

HAKEDA, YOSHIYUKI, HOTTA, TAKAHIKO, KURIHAR, ANORIYOSHI, IKEDA, EIKO, MAEDA, NORIHIKO, YAGYU, YOSHIHIRO, KUMEGAWA, MASAYOSHI

Journal:

Year:

1987

Language:

english

File:

PDF, 1.08 MB

english, 1987

44

Mouse Osteoblastic Cells (MC3T3-E1) at Different Stages of Differentiation Have Opposite Effects on Osteoclastic Cell Formation

HIURA, KENJI, SUMITANI, KOJI, KAWATA, TERUSHIGE, HIGASHINO, KIYOSHI, OKAWA, MAMORU, SATO, TAKUYA, HAKEDA, YOSHIYUKI, KUMEGAWA, MASAYOSHI

Journal:

Year:

1991

Language:

english

File:

PDF, 1.10 MB

english, 1991

45

Prostaglandin F 2α Stimulates Tyrosine Phosphorylation and Mitogen-Activated Protein Kinase in Osteoblastic MC3T3-E1 Cells via Protein Kinase C Activation

Hakeda, Yoshiyuki, Shiokawa, Miho, Mano, Hiroshi, Kameda, Takashi, Raisz, Lawrence G., Kumegawa, Masayoshi

Journal:

Year:

1997

Language:

english

File:

PDF, 4.36 MB

english, 1997

46

Biological Activity Assessment of lα,25- Dihydroxyvitamin D 3 -26,23-Lactone and Its Intermediate Metabolites in Vivo and in Vitro

ISHIZUKA, SEIICHI, SUMITANI, KOJI, HIURA, KENJI, KAWATA, TERUSHIGE, OKAWA, MAMORU, HAKEDA, YOSHIYUKI, KUMEGAWA, MASAYOSHI

Journal:

Year:

1990

Language:

english

File:

PDF, 893 KB

english, 1990

47

The polymethoxy flavonoid sudachitin suppresses inflammatory bone destruction by directly inhibiting osteoclastogenesis due to reduced ROS production and MAPK activation in osteoclast precursors

Ohyama, Yoko, Ito, Junta, Kitano, Victor J., Shimada, Jun, Hakeda, Yoshiyuki, Reddy, Sakamuri V.

Journal:

Year:

2018

Language:

english

File:

PDF, 15.04 MB

english, 2018

48

Effect of Glucocorticoids on Induction of Fructose Bisphosphatase and Glucose-6-Phosphatase in Fetal Mouse Liver

TASHIMA, Yohtalou, MIZUNUMA, Hideo, SHIMA, Hiroshi, KOBAYASHI, Ryoji, HAKEDA, Yoshiyuki, MAEDA, Norihiko, KUMEGAWA, Masayoshi

Journal:

Journal of Biochemistry

Year:

1984

Language:

english

File:

PDF, 381 KB

english, 1984

49

LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells

Kitano, Victor J. F., Ohyama, Yoko, Hayashida, Chiyomi, Ito, Junta, Okayasu, Mari, Sato, Takuya, Ogasawara, Toru, Tsujita, Maki, Kakino, Akemi, Shimada, Jun, Sawamura, Tatsuya, Hakeda, Yoshiyuki

Journal:

Journal of Cell Science

Year:

2020

File:

PDF, 3.68 MB

2020

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